Neurology and Regenerative Medicine Solutions
Tissue scaffolds are implantable textile components that act as matrices for cellular growth and are critically important in the fields of tissue engineering, regenerative medicine and neurology. Scaffolds, made from polymeric material, provide a framework that cells can attach to and proliferate. Commonly associated with non-wovens, the unique patterns of the scaffold structure can be engineered to be highly attractive to anchor-dependent cells. At ATEX, we can control the shape, elasticity, rigidity, and surface characteristics of the scaffold among other attributes so that we can optimize the matrix for specific cell growth requirements such as nerve regeneration.
This is a class of products that plays an important role in preventing stroke after procedures such as TAVR. An embolic protection device acts as a physical barrier, preventing particles and debris from traveling to the brain, lungs, and kidneys where they can occlude critical passageways for blood and oxygen. Such occlusions can lead to difficulty breathing, stroke and, in severe cases, even death. ATEX Technologies can provide highly engineered woven or knit implantable textile components that can facilitate the capture of these particles by precisely controlling pore size, material type and overall dimensions. The key in engineering high performing textiles for this application is to manufacture medical textiles that can capture particles of many sizes effectively while also allowing for the flow of blood through the “filter”.
A Thrombus Retrieval component acts to capture and remove occlusions, or clots, from vessels leading to the brain or heart. Some of the least invasive procedures for thrombus removal are textile based since implantable textiles can be compressed to accommodate the delivery system and then expanding once deployed at the site of the occlusion. ATEX Technologies works with device manufacturers collaboratively to determine exactly how the textile’s properties (density, porosity, expandability, compaction, and flexibility) can all be defined in such a way as to impart very specific performance attributes to the textile so that it can perform its function effectively and safely.
A hollow tube made from textile can play an integral role in tissue engineering, regenerative medicine and neurology by promoting the growth of nerve cells. By isolating the neural fibers and guiding their growth, it is possible to create a pathway for budding axons to grow together, creating the opportunity for the severed nerve ends to re-establish communication.